Vaccines play an important role in keeping us healthy, by reducing the risk of infection. The vaccine works with with our natural immune system to build defenses and immunity to a specific disease. When germs (either a bacteria or virus) invade the body, they attack and multiply. This is called an infection. In response, the body’s immune system, a network of cells, tissues and organs, work together to protect your body and get rid of the infection. If the germ is new or foreign to your immune system, it make take several days for your immune system to act, as it is learning how to fight off the infection. Because your immune system has a great memory, if the germ comes back, your immune system will be able to fight it off faster, keeping you healthier and happier.

When you get a vaccine, it imitates an infection which allows the immune system to develop immunity. The vaccine rarely causes illness since it is a small amount of weak or dead germs that can cause the disease. This allows the immune system to produce antibodies and prepare your body to fight the disease faster and more effectively. This way you won’t get sick or reduce the severity of the symptoms.

There are several different types of vaccines:

  • A Live Vaccine fight viruses and bacteria. These vaccines contain a version of the living virus or bacteria that has been weakened so it does not cause serious disease in people with a healthy immune system. Since this type of vaccine is closest the “real” infection, it is the best teacher for your immune system. An example of this type is the MMR (measles, mumps and rubella) vaccine or the Chickenpox vaccine.
  • An Inactivated Vaccine also fight viruses and bacteria. The vaccine includes germs which are killed (or inactive). Since the vaccine produces an immune response which is slower than a live vaccine, often times multiple doses are necessary to build up and maintain immunity. An example of this type of vaccine would be the polio vaccine.
  • A Toxoid Vaccine prevents diseases caused by bacteria that produce toxins in the body. When the immune system receives a vaccine containing a toxoid, the immune system learns to fight off the natural toxin should you come into contact with it. An example of this type would be the diphtheria and tetanus vaccine.
  • A Subunit Vaccine, similar to the inactivated vaccine, this vaccine doesn’t contain live components of a virus or bacteria. It contains only specific parts of the germ (also scientifically known as an antigen) that is necessary to teach your immune system how to fight off the virus. Side effects for this type of vaccine is less common, as it is not give the whole germ.   An example of this would be the Whooping Cough Vaccine.
  • A Conjugate Vaccines fights off a different type of bacteria. Bacteria can sometimes go unnoticed by your immune system by disguising themselves. This make it hard for your immune system to recognize and respond to the bacteria. The vaccine gives information to recognize the disguised bacteria to your immune system. Therefore, letting your immune system react and develop a response. An example of this type of vaccine is the Hib vaccine.

While vaccines work in different ways, they all have an important task in keeping us healthy. Medical advancements for vaccines are an important part of continuing to keep us healthy.  Research is about finding out new knowledge that could lead to changes in treatment, or care. This new knowledge give investigational vaccines the potential to have greater protection to disease and update current ones to be more effective and safe. If you would like to be a part of a community of research heroes, and would like to participate in a vaccine research study, give us a call today at 585-288-0890.

Dengue Fever Vaccine Study

Rochester Clinical Research is currently seeking participants between the ages of 18-50 years old to participate in a Dengue Fever vaccine study. The study is 1 year long and consists of 8 visits to our office. You will be compensated up to $150 per visit for your time and travel to participate.

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Ages 18 – 50
Compensation* $150 per visit
Study Topics Dengue Fever

*Compensation for time and travel may be available to those who qualify.

Flu Vaccine Study

Rochester Clinical Research is looking for volunteers 65 years or older to participate in a flu vaccine research study. The study is approximately 12 months long and consists of 5 to 7 visits to our office. You will be compensated $165 per visit for your time and travel to participate.

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Ages 65+
Compensation* $165 Per Visit
Study Topics Vaccines

*Compensation for time and travel may be available to those who qualify.

Varicella Vaccine Study

Rochester Clinical Research is currently looking for individuals to join a vaccine study for the varicella-zoster virus. Varicella is one of nine in the herpes class that can infect humans and causes chickenpox or shingles infections when it’s not prevented. The purpose of this study is to evaluate the safety and effectiveness of an mRNA vaccine against the virus. We are seeking participants between the ages of 50-69 years old who have not received a shingles vaccine already. This study is between 8-12 months long and includes at least 10 office visits. Compensation is available for $128 per office visit.

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Ages 50 – 69
Compensation* $128 per visit and $5 per diary entry
Study Topics Vaccines

*Compensation for time and travel may be available to those who qualify.

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CMV Adolescents Vaccine Study

Rochester Clinical Research is currently seeking volunteers between the ages of 9-25 years old to participate in a preventative CMV vaccine study. The purpose of this study is to vaccinate children against the virus to prevent them from spreading it to adults, especially women that may be planning on becoming pregnant in the foreseeable future. The study is approximately 18 months long and includes 12 visits in total.

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Ages 9 – 25
Compensation* $1,809
Study Topics Vaccines

*Compensation for time and travel may be available to those who qualify.

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Pediatric Lyme Disease Vaccine Study

There is currently no vaccine to prevent or protect against Lyme. RCR is currently conducting a vaccine study to help prevent Lyme disease from infecting adolescents between the ages of 5 to 17. This study will last approximately 24 months with 6 visits to our RCR office and 2 telephone calls. 

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Ages 5 – 17
Compensation* $125 per visit
Study Topics Vaccines

*Compensation for time and travel may be available to those who qualify.

RSV Vaccine Study

Rochester Clinical Research is currently seeking volunteers ages 50-59 years of age, who are at risk for chronic asthma/COPD, cardiovascular health hx, stroke/HA, and diabetes, to participate in an RSV (respiratory syncytial virus) vaccine study. This paid research study is testing the immune response and safety of a phase 3 vaccine. The study is about 12 months long and requires 4 visits to our office. If you qualify, you may be compensated for your time and travel to participate in the study.

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Ages 50 – 59
Compensation* TBD
Study Topics Vaccines

*Compensation for time and travel may be available to those who qualify.

Flu Vaccine Trial

Rochester Clinical Research is currently seeking volunteers who are 65 years and older for an Influenza vaccine study. The purpose of this study will be to evaluate the safety and immunogenicity of an mRNA vaccine to prevent influenza. Compensation for time and travel is available for around $630 to those who qualify.

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Ages 65+
Compensation* Around $500
Study Topics Vaccines

*Compensation for time and travel may be available to those who qualify.

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mRNA Flu Vaccine Study

Rochester Clinical Research is seeking volunteers who are 65 years and older to participate in an investigational mRNA flu vaccine study. The purpose of this study is to evaluate the effectiveness of using mRNA technology in an investigational flu vaccine and see if it protects against different variants. This is a phase 3 study and is about 12 months long with only one visit to our office.

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Ages 65+
Compensation* $834
Study Topics Vaccines

*Compensation for time and travel may be available to those who qualify.

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CMV Vaccine

Rochester Clinical Research is currently seeking born-female volunteers between the ages of 16 and 40 years old to participate in a CMV vaccine study. The purpose of this study is to find a safe and effective vaccine against Cytomegalovirus.

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Ages 16 – 40
Gender For female patients only
Study Topics Vaccine