Vaccines play an important role in keeping us healthy, by reducing the risk of infection. The vaccine works with with our natural immune system to build defenses and immunity to a specific disease. When germs (either a bacteria or virus) invade the body, they attack and multiply. This is called an infection. In response, the body’s immune system, a network of cells, tissues and organs, work together to protect your body and get rid of the infection. If the germ is new or foreign to your immune system, it make take several days for your immune system to act, as it is learning how to fight off the infection. Because your immune system has a great memory, if the germ comes back, your immune system will be able to fight it off faster, keeping you healthier and happier.

When you get a vaccine, it imitates an infection which allows the immune system to develop immunity. The vaccine rarely causes illness since it is a small amount of weak or dead germs that can cause the disease. This allows the immune system to produce antibodies and prepare your body to fight the disease faster and more effectively. This way you won’t get sick or reduce the severity of the symptoms.

There are several different types of vaccines:

  • A Live Vaccine fight viruses and bacteria. These vaccines contain a version of the living virus or bacteria that has been weakened so it does not cause serious disease in people with a healthy immune system. Since this type of vaccine is closest the “real” infection, it is the best teacher for your immune system. An example of this type is the MMR (measles, mumps and rubella) vaccine or the Chickenpox vaccine.
  • An Inactivated Vaccine also fight viruses and bacteria. The vaccine includes germs which are killed (or inactive). Since the vaccine produces an immune response which is slower than a live vaccine, often times multiple doses are necessary to build up and maintain immunity. An example of this type of vaccine would be the polio vaccine.
  • A Toxoid Vaccine prevents diseases caused by bacteria that produce toxins in the body. When the immune system receives a vaccine containing a toxoid, the immune system learns to fight off the natural toxin should you come into contact with it. An example of this type would be the diphtheria and tetanus vaccine.
  • A Subunit Vaccine, similar to the inactivated vaccine, this vaccine doesn’t contain live components of a virus or bacteria. It contains only specific parts of the germ (also scientifically known as an antigen) that is necessary to teach your immune system how to fight off the virus. Side effects for this type of vaccine is less common, as it is not give the whole germ.   An example of this would be the Whooping Cough Vaccine.
  • A Conjugate Vaccines fights off a different type of bacteria. Bacteria can sometimes go unnoticed by your immune system by disguising themselves. This make it hard for your immune system to recognize and respond to the bacteria. The vaccine gives information to recognize the disguised bacteria to your immune system. Therefore, letting your immune system react and develop a response. An example of this type of vaccine is the Hib vaccine.

While vaccines work in different ways, they all have an important task in keeping us healthy. Medical advancements for vaccines are an important part of continuing to keep us healthy.  Research is about finding out new knowledge that could lead to changes in treatment, or care. This new knowledge give investigational vaccines the potential to have greater protection to disease and update current ones to be more effective and safe. If you would like to be a part of a community of research heroes, and would like to participate in a vaccine research study, give us a call today at 585-288-0890.

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Pneumococcal and Flu Vaccine Study

Rochester Clinical Research is currently seeking volunteers to participate in a pneumococcal and flu vaccine study. This study is for people who are 50 years or older and want to protect themselves against these two very contagious viruses before the Winter season. This study is approximately 7 months long and consists of 3 office visits and 4 telephone call check-ins. The purpose of the study is to test the safety and efficacy of the vaccine targeting the two viruses and different stains of the flu. If you qualify to participate, compensation will be provided for your time and travel.

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Ages 50+
Compensation* $250
Study Topics Vaccines

*Compensation for time and travel may be available to those who qualify.

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Flu Vaccine Trial

Rochester Clinical Research is currently seeking volunteers who are 18 years and older for an Influenza vaccine study. The purpose of this study will be to evaluate the safety and immunogenicity of an mRNA vaccine to prevent influenza. Compensation for time and travel is available for around $630 to those who qualify.

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Ages 18+
Compensation* Around $630
Study Topics Vaccines

*Compensation for time and travel may be available to those who qualify.

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Covid-19 Omicron Variant Vaccine Trial

Rochester Clinical Research is currently seeking volunteers over the age of 18 to participate in an omicron variant booster vaccine study. This paid research study is testing the efficacy and tolerability of an omicron variant-specific vaccine. The purpose of this vaccine is to provide extra protection against the highly contagious strain. The study is about 6 months long and requires 5 visits to the office.

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Ages 18+
Compensation* TBD (Waiting on contracts)
Study Topics Vaccines

*Compensation for time and travel may be available to those who qualify.

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mRNA Flu Vaccine Study

Rochester Clinical Research is seeking volunteers who are 50 years and older to participate in an mRNA flu vaccine study. The purpose of this study is to evaluate the effectiveness of using mRNA technology in a flu vaccine at protecting against different variants. Since the normal flu vaccines are only about 60% effective, doctors believe that this will result in better protection results. This is a phase 3 study and is about 12 months long with only one visit to our office.

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Ages 50+
Study Topics Vaccines

Pneumococcal Vaccine Study

Rochester Clinical Research is now seeking volunteers between the ages of 18 and 49 years old for a Pneumococcal vaccine study. This paid research study hopes to find a new pneumococcal vaccine that will potentially protect against strains not covered by the currently available vaccines. The study is approximately 6 months long and you can get up to $555 in study-related compensation.

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Ages 18 – 49
Compensation* $555
Study Topics Vaccines

*Compensation for time and travel may be available to those who qualify.

Chikungunya Vaccine Study

Rochester Clinical Research is participating in a study evaluating the immune response of a single dose of the Chikungunya vaccine in healthy adolescents between the ages of 12 and 17 years old. The study will last approximately 6 months with 7 visits to our office. Compensation is available for up to $650 for time and travel, for those who qualify.

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Ages 12 – 17
Compensation* $650
Study Topics Chikungunya Virus

*Compensation for time and travel may be available to those who qualify.

Dengue Fever Vaccine Study

Dengue fever is a virus that is carried by mosquitoes, usually in subtropical and tropical climates. Symptoms can range from either being mild or severe. The virus only lasts about a week, but if left untreated it could turn into severe symptoms. We are conducting a phase 2 study of a vaccine for people ages 18-50 years old to test the safety and efficiency of different doses given. It’s a one-year-long trial with 8 visits to the office.

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Ages 18 – 50
Compensation* $120 per visit
Study Topics Dengue Fever

*Compensation for time and travel may be available to those who qualify.

Chikungunya Vaccine Study

Chikungunya is a virus that can be spread through mosquito bites similar to other mosquito-spread illnesses like Zika, malaria, dengue, and West Nile Virus. RCR is conducting a study to test the effectiveness of a phase 3 vaccine to prevent Chikungunya in people who are 65 or older. The study will be 7 months long and consists of 5 office visits and 2 phone call appointments.

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Ages 65+
Compensation* $900
Study Topics Chikungunya Virus

*Compensation for time and travel may be available to those who qualify.

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Flu Vaccine Study

Rochester Clinical Research is now seeking volunteers between the ages of 65 and 85 years old for an influenza vaccine study. The purpose of this research study is to evaluate the safety and effectiveness of an investigational influenza vaccine versus a currently approved influenza vaccine.

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Ages 65 – 85
Compensation* $625
Study Topics Flu Vaccine

*Compensation for time and travel may be available to those who qualify.

COVID booster plus Influenza Vaccine Study

Rochester Clinical Research is now enrolling volunteers between the ages of 18 and 75 years old for an investigational COVID vaccine booster plus flu vaccine study.

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Ages 18 – 75
Study Topics Vaccine

Migraine Relief Study

Rochester Clinical Research wants to help advance treatments for people who suffer from episodic migraines. We are conducting a study that is three months long and requires you to come in once a month to receive an injection. RCR is seeking healthy individuals between the ages of 18-65 who get 4-14 migraines a month to participate. This is a phase 4 study and Rochester Clinical research wants to help get this treatment FDA-approved so that people no longer have to let migraines slow down their day.

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Ages 18 – 65
Compensation* TBD (Waiting on contracts)
Study Topics Migraine

*Compensation for time and travel may be available to those who qualify.

COVID-19 Booster Vaccine

Rochester Clinical Research is seeking volunteers over the age of 18 for a COVID-19 vaccine study to potentially protect against specific variants of COVID-19.

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Ages 18 – 85
Compensation* $150 per visit
Study Topics Vaccine

*Compensation for time and travel may be available to those who qualify.

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CMV Vaccine

Rochester Clinical Research is currently seeking born-female volunteers between the ages of 16 and 40 years old to participate in a CMV vaccine study. The purpose of this study is to find a safe and effective vaccine against Cytomegalovirus.

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Ages 16 – 40
Gender For female patients only
Study Topics Vaccine
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RSV Vaccine Study

Rochester Clinical Research is currently seeking adults over the age of 64 years old for different RSV vaccine studies. Join an RSV vaccine study that is testing the efficacy of a vaccine that may prevent lower respiratory tract disease, which is associated with the RSV virus. The study will last about 24 to 30 months and consists up to 6 office visit and a monthly telephone appointment. Compensation may be up to $1,640 for time and travel to participate in the study. 

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Ages 65+
Compensation* $1,640
Study Topics Vaccine

*Compensation for time and travel may be available to those who qualify.