Vaccines play an important role in keeping us healthy, by reducing the risk of infection. The vaccine works with with our natural immune system to build defenses and immunity to a specific disease. When germs (either a bacteria or virus) invade the body, they attack and multiply. This is called an infection. In response, the body’s immune system, a network of cells, tissues and organs, work together to protect your body and get rid of the infection. If the germ is new or foreign to your immune system, it make take several days for your immune system to act, as it is learning how to fight off the infection. Because your immune system has a great memory, if the germ comes back, your immune system will be able to fight it off faster, keeping you healthier and happier.

When you get a vaccine, it imitates an infection which allows the immune system to develop immunity. The vaccine rarely causes illness since it is a small amount of weak or dead germs that can cause the disease. This allows the immune system to produce antibodies and prepare your body to fight the disease faster and more effectively. This way you won’t get sick or reduce the severity of the symptoms.

There are several different types of vaccines:

  • A Live Vaccine fight viruses and bacteria. These vaccines contain a version of the living virus or bacteria that has been weakened so it does not cause serious disease in people with a healthy immune system. Since this type of vaccine is closest the “real” infection, it is the best teacher for your immune system. An example of this type is the MMR (measles, mumps and rubella) vaccine or the Chickenpox vaccine.
  • An Inactivated Vaccine also fight viruses and bacteria. The vaccine includes germs which are killed (or inactive). Since the vaccine produces an immune response which is slower than a live vaccine, often times multiple doses are necessary to build up and maintain immunity. An example of this type of vaccine would be the polio vaccine.
  • A Toxoid Vaccine prevents diseases caused by bacteria that produce toxins in the body. When the immune system receives a vaccine containing a toxoid, the immune system learns to fight off the natural toxin should you come into contact with it. An example of this type would be the diphtheria and tetanus vaccine.
  • A Subunit Vaccine, similar to the inactivated vaccine, this vaccine doesn’t contain live components of a virus or bacteria. It contains only specific parts of the germ (also scientifically known as an antigen) that is necessary to teach your immune system how to fight off the virus. Side effects for this type of vaccine is less common, as it is not give the whole germ.   An example of this would be the Whooping Cough Vaccine.
  • A Conjugate Vaccines fights off a different type of bacteria. Bacteria can sometimes go unnoticed by your immune system by disguising themselves. This make it hard for your immune system to recognize and respond to the bacteria. The vaccine gives information to recognize the disguised bacteria to your immune system. Therefore, letting your immune system react and develop a response. An example of this type of vaccine is the Hib vaccine.

While vaccines work in different ways, they all have an important task in keeping us healthy. Medical advancements for vaccines are an important part of continuing to keep us healthy.  Research is about finding out new knowledge that could lead to changes in treatment, or care. This new knowledge give investigational vaccines the potential to have greater protection to disease and update current ones to be more effective and safe. If you would like to be a part of a community of research heroes, and would like to participate in a vaccine research study, give us a call today at 585-288-0890.

Chikungunya Vaccine Study

Rochester Clinical Research is participating in a study evaluating the immune response of a single dose of the Chikungunya vaccine in healthy adolescents between the ages of 12 and 17 years old. The study will last approximately 6 months with 7 visits to our office. Compensation is available for up to $650 for time and travel, for those who qualify.

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Ages 12 – 17
Compensation* $650
Study Topics Chikungunya Virus

*Compensation for time and travel may be available to those who qualify.

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Dengue Fever Vaccine Study

Dengue fever is a virus that is carried by mosquitoes, usually in subtropical and tropical climates. Symptoms can range from either being mild or severe. The virus only lasts about a week, but if left untreated it could turn into severe symptoms. We are conducting a phase 2 study of a vaccine for people ages 18-50 years old to test the safety and efficiency of different doses given. It’s a one-year-long trial with 8 visits to the office.

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Ages 18 – 50
Compensation* $120 per visit
Study Topics Dengue Fever

*Compensation for time and travel may be available to those who qualify.

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Chikungunya Vaccine Study

Chikungunya is a virus that can be spread through mosquito bites similar to other mosquito-spread illnesses like Zika, malaria, dengue, and West Nile Virus. RCR is conducting a study to test the effectiveness of a phase 3 vaccine to prevent Chikungunya in people who are 65 or older. The study will be 7 months long and consists of 5 office visits and 2 phone call appointments.

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Ages 65+
Compensation* $900
Study Topics Chikungunya Virus

*Compensation for time and travel may be available to those who qualify.

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Dengue Fever Vaccine Study

Dengue fever is a virus that is carried by mosquitoes, usually in subtropical and tropical climates. There currently isn’t a vaccine for adults, only children who are between the ages of 9-16. We are conducting a phase 2 study of a vaccine for people ages 18-50 years old to test the safety and efficiency of different doses given. It’s a one-year-long trial with 8 visits to the office.

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Ages 18 – 50
Compensation* $120 per visit
Study Topics Dengue Fever

*Compensation for time and travel may be available to those who qualify.

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Lyme Disease Vaccine Study

There currently isn’t a vaccine out there to protect against Lyme disease. RCR is conducting a study testing the safety and efficacy of a phase 3 vaccine to help prevent Lyme disease. This study will last approximately 3 years with 7 visits to our RCR office along with 1 phone call appointment. We are seeking individuals who are 5 years and older to participate in the study.

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Ages 5+
Compensation* $1,090
Study Topics Lyme Disease Vaccine

*Compensation for time and travel may be available to those who qualify.

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Flu Vaccine Study

Rochester Clinical Research is now seeking volunteers between the ages of 65 and 85 years old for an influenza vaccine study. The purpose of this research study is to evaluate the safety and effectiveness of an investigational influenza vaccine versus a currently approved influenza vaccine.

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Ages 65 – 85
Compensation* $625
Study Topics Flu Vaccine

*Compensation for time and travel may be available to those who qualify.

COVID booster plus Influenza Vaccine Study

Rochester Clinical Research is now enrolling volunteers between the ages of 18 and 75 years old for an investigational COVID vaccine booster plus flu vaccine study.

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Ages 18 – 75
Study Topics Vaccine

Pneumococcal Vaccine Study

Rochester Clinical Research is now seeking volunteers between the ages of 50 and 64 years old for a research study to evaluate the safety and efficacy of an investigational Pneumococcal vaccine.

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Ages 50 – 64
Compensation* $937.50
Study Topics Vaccine

*Compensation for time and travel may be available to those who qualify.

COVID-19 Vaccine Booster Study Interest List

If you are interested in continuing to advance our protection from COVID-19 and would like to potentially participate in a future booster study designed to protect against specific variants, submit your information to be added to our COVID-19 Vaccine Booster Study interest list.

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COVID-19 Vaccine

Rochester Clinical Research is seeking volunteers over the age of 18 for a COVID-19 vaccine study to potentially protect against specific variants of COVID-19.

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Ages 18 – 85
Study Topics Vaccine

COVID booster plus Pneumococcal Vaccine Study

Rochester Clinical Research is seeking volunteers 50 years old and up for a study to evaluate the safety and effectiveness of a combination pneumococcal and COVID vaccine.

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Ages 50+
Study Topics Vaccine

Chikungunya Vaccine

Rochester Clinical Research is seeking volunteers between 12 to 17 years old for a study to evaluate the safety and effectiveness of a Chikungunya Vaccine in healthy adults.

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Ages 12 – 17
Compensation* $650
Study Topics Vaccine

*Compensation for time and travel may be available to those who qualify.

COVID Vaccine Booster Plus Flu Vaccine

Rochester Clinical Research is seeking volunteers over the age of 18 for a clinical trial that will be investigating the safety and effectiveness of a COVID-19 vaccine booster in conjunction with an influenza vaccine.

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Ages 18+
Study Topics Vaccine

COVID-19 Vaccine Booster

Rochester Clinical Research is seeking volunteers between the ages of 18-59 for a study to evaluate the safety and effectiveness of a COVID-19 vaccine booster.

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Ages 18
Study Topics Vaccine
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CMV Vaccine

Rochester Clinical Research is currently seeking born-female volunteers between the ages of 16 and 40 years old to participate in a CMV vaccine study. The purpose of this study is to find a safe and effective vaccine against Cytomegalovirus.

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Ages 16 – 40
Gender For female patients only
Study Topics Vaccine

RSV Vaccine Study

If you are interested in helping find a vaccine to prevent RSV, and want to join a future RSV trial at RCR join our interest list!

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Study Topics Vaccine

Yellow Fever Vaccine

Rochester Clinical Research is currently seeking volunteers between the ages of 12 and 60 years old to participate in a Yellow Fever Vaccine study. The purpose of this study is to assess the immune response of the investigational vaccine as compared to the currently approved Yellow Fever vaccine.

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Ages 12 – 60
Compensation* $875
Study Topics Vaccine

*Compensation for time and travel may be available to those who qualify.

RSV Vaccine Study

RCR is currently seeking the help of volunteers over the age of 60 to participate in a study looking at the effectiveness of a vaccine for RSV.

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Ages 60+
Study Topics Vaccine

COVID-19 Vaccine Trial

Rochester Clinical Research is currently seeking volunteers over the age of 18 years old for a COVID-19 Vaccine research study.

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Ages 18+
Compensation* $1,200-$1,500
Study Topics COVID-19 Vaccine

*Compensation for time and travel may be available to those who qualify.