About The Study

Today, 13% of the US population are 65 and older and more than half of them have knee pain from osteoarthritis in at least 1 joint. By 2020, 20% of Americans will have passed their 65th birthday and will be at risk of knee pain caused by osteoarthritis.  Osteoarthritis of the knee wears and tears at your cartilage, a cushion and protector between your bones, until the cartilage is gone. This leaves your bones grinding up against each other causing pain, swelling or even the knee to lock or stick during movement. The exact cause of this is unknown but is associated with aging and normal wear and tear on your knee.

Currently, the therapies to treat knee pain from osteoarthritis are limited. Most current treatments are only designed to relieve pain and reduce the disability caused by bone and cartilage degeneration. Drug therapies target the symptoms but not the cause of the disease.

Rochester Clinical Research is currently enrolling individuals between the ages of 40 – 80 for a research study of a new study drug aimed at reversing the degenerative changes in your cartilage and bone.  The study drug would be administered through a single injection in the knee with the most pain. The study would last approximately up to 56 weeks with 9 visits to our office. Compensation is available for time and travel up to $675, for those who qualify.  Health insurance is not required to participate in this study and we will pay for the X-rays needed throughout the study, if qualified.


  • Be 40 – 80 years old
  • History of knee pain for at least 6 months
  • Never have had a knee or hip replacement
  • Not have any scheduled surgeries during the study
  • *Please note, other conditions may apply