About the Study

Osteoarthritis (OA) of the knee is extremely common and debilitating for more than 30 million adults in the US. OA wears and tears at the cartilage, a cushion and protector between your bones, until the cartilage is gone. This leaves your bones grinding up against each other and causing pain, swelling, or even the knee to lock or stick during movement.

Rochester Clinical Research is currently enrolling volunteers to study a new investigational drug administered orally once daily in patients with knee osteoarthritis. The drug is aimed at reducing cartilaginous degradation and hopefully improve pain and function in the arthritic knee.

Compensation for time and travel may be available for qualified participants up to $575. Health insurance is not required to participate in this study, and we will pay for our MRI’s and X-Rays throughout the study, if qualified.


  • Are you between the ages of 40 and 75?
  • Are you willing to get 3 MRI’s of the knee (free of charge)?
  • Are you willing to get 2 X-Rays of the knee (free of charge)?
  • Do you have a BMI less than 40 kg/m2?
  • Do you have a history of knee pain for at least six months?
  • *Please note, other conditions may apply