About the Study:

Nearly 94 million U.S. adults age 20 or older have total cholesterol levels higher than 200 mg/dL. Twenty-eight million adults in the United States have total cholesterol levels higher than 240 mg/dL. Having high blood cholesterol raises the risk for heart disease, the leading cause of death, and for stroke, the fifth leading cause of death.

Rochester Clinical Research is now enrolling volunteers over the age of 40 with an established cardiovascular disease with a history of heart attack, Stroke or symptoms of Peripheral Artery Disease for a clinical trial for a new treatment to be taken in addition to a high-intensity statin.

Volunteers for this study will need to be currently on a well-tolerated high dose statin drug in order to qualify. High dose would mean greater than 40 mg of Atorvastatin (also known as Lipitor) or a greater than 20 mg of rosuvastatin (also known as Crestor) every day.

The purpose of this study will be to observe if this new treatment taken in addition to a statin will lower the incidence of myocardial infarction (heart attack), stroke and cerebral vascular death in patients with high cholesterol and history of cardiovascular disease.

This study will last between 5 and 6 years with approximately 15 visits to our office.

To qualify for this study you must be 40 years of age or older, have a fasting LDL greater than 70 mg/dl, be currently on a stable dose for more than 4 weeks of a well-tolerated lipid lowering regimen with either Atorvastatin greater than 40 mg every day which is commonly known as Lipitor (or the generic brand) or rosuvastatin greater than 20 mg every day and have an established Cardiovascular Disease with a history of ANY of the following: Myocardial Infarction, Stroke or symptoms of peripheral artery disease.

Compensation is available for time and travel up to $100 per in-person visit, for those who qualify. Study related care is available to participants at no cost and health insurance is not required nor needed.

Qualifications

  • 40 years of age or older
  • Have a fasting LDL greater than 70 mg/dl
  • Currently taking over 40 mg of Atorvastatin (Lipitor) every day OR over 20 mg Rosuvastatin every day (Crestor) for at least 4 weeks
  • Have an established Cardiovascular Disease with a history of ANY of the following : Myocardial Infarction (heart attack), Stroke or symptoms of Peripheral Artery Disease
  • Please note, other conditions may apply