About the Study

E. Coli bacteria normally live in the intestines of health people and animals. Most varieties of E Coli are harmless, however there are a few strains that can cause severe abdominal cramps, diarrhea and vomiting. E Coli can also cause bacteremia and bloodstream infections (sepsis). These infections generally occur in the elderly who are already contending with multiple medical problems, which has a significant morbidity and mortality associated with bacteremia. There is also a worldwide emergence of multi-drug-resistant strains making therapy more challenging. The study vaccine would cover 10 of the most problematic subtypes of E Coli. These also tend to be the subtypes where drug resistance is developing.

Rochester Clinical Research is currently enrolling individuals between the ages of 60-85 who are generally healthy. The study is to evaluate the safety and effectiveness of the study vaccine that may protect against E Coli that could cause sepsis. Compensation is available up to $300 for time and travel for those who qualify.


  • Ages 60-85 years old
  • Generally Healthy
  • *Please note, other conditions may apply.