What is this study all about?

Clostridium difficile, also known as C. diff, is one of the most commonly recognized causes of infectious diarrhea in healthcare settings.  As many as 50% or more of hospital patients are carriers of C. diff infection but do not have any symptoms. While C. diff is a type of bacteria that lives in the human intestines, spreading the infection is easy in a healthcare setting as it can survive outside of the body for several months. C. diff is very hard to kill and people can become infected by touching surfaces that are contaminated or by coming into contact with a healthcare worker that has the bacteria on their hands.

In the last decade, the number and severity of C. diff outbreaks in hospitals and nursing homes have increased.  Because of the increasing burden of C. diff on patients and the health care system, we are currently enrolling patients over the age of 60 in a C. diff vaccine research study. The purpose of the study is to evaluate the safety and tolerability of a multiple dose vaccine to protect against C. diff. The study will last approximately 12 months with 5 visits to our office and 1 telephone call.

Health insurance is not required or needed and all study related care is provided. Compensation is available for time and travel up to $250 for those who qualify.

Qualifications

  • Are 50 years old or over
  • Have had at least 2 visits to the emergency room, or had a hospitalization of at least 2 nights in the last 12 months, or
  • Have a planned hospitalization that will require a stay of 2 or more nights or
  • Are a resident in a nursing facility or
  • Have had at least 10 outpatient visits in the last 12 months or
  • Have received oral or injectable antibiotics within the last 12 weeks.
  • **Please note, other conditions may apply**