Lyme Vaccine Study

Lyme disease is a tick-borne disease. It can cause rash and flu like symptoms. Untreated, Lyme disease can produce a wide range of symptoms depending on the stage of the infection. This can include fever, rash, facial paralysis, and arthritis with severe joint pain and swelling. Early signs and symptoms may include a small red bump followed by a bullseye rash. Because symptoms can be confused with other infections, early diagnosis is often difficult. Bloodwork suggesting infection may also be negative in the early phases of the illness.

Because Lyme infection can be so difficult to detect and treat, prevention with a vaccine would be a better approach to controlling the disease.  In the Northeast, especially New York State, Lyme disease has increased steadily over the past 25 years, according to the CDC. And is now the most commonly reported vector borne illness in the United States.

Rochester Clinical Research is currently seeking healthy adults to participate in a study that will last approximately 19 months and require 12-14 office visits.

Compensation will be available for time and travel but is still being determined, for those who qualify. Study related care is available to participants at no cost and health insurance is not required nor needed.


  • Between the ages of 18-70
  • BMI between 19-39
  • Haven't been treated for Lyme in the past 3 months or had a tick bite in the last 4 weeks
  • Cannot have previously participated in a Lyme Disease vaccine trial
  • Please note, other conditions may apply.