Help Future Generations, Today

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Fall is a favorite season for many people. From pumpkin spice, to everything nice, fall definitely has it’s charm. However, as the seasons change and the weather get colder, more people get sick. While many think it is the cold weather, it is actually because a virus can replicate and spread most effectively when the air is cold and dry.

The Respiratory syncytial virus, also known as RSV, causes infections of the lungs and respiratory tract. The virus enters the body through the eyes, nose or mouth – most likely when someone coughs or sneezes near you or shakes your hand. The virus can also live for hours on hard objects such as counter tops, toys, railings and more. If you touch your mouth, nose, or eyes after touching a contaminated object, you could pick up the virus.

Most healthy adults will get RSV and experience mild cold-like signs and symptoms, such as including runny nose, dry cough, sore throat or a mild headache. However, RSV can cause severe infection in some people, especially pre-mature babies, older adults, infants or anyone with a weak immune system. Each year in the United States (according to the CDC), an estimated 57,000 children younger than 5 years old are hospitalized due to an RSV infection. Those at greatest risks are pre-mature babies,  and very young infants, especially those 6 months and younger. One to two out of every 100 children younger than 6 months of age with RSV infection may need to be hospitalized according to the CDC.  Those who are hospitalized may require oxygen, intubation and or mechanical ventilation (help with breathing) due to more severe symptoms including bronchiolitis, inflammation of the small airways in the lung, or pneumonia, infection of the lungs.

Right now, there is no vaccine to prevent RSV infection, but pharmaceutical companies and Rochester Clinical Research is working hard to develop and get one approved. If you would like to help with the advancement of medicine, specifically to help protect our future generations against RSV, we encourage you to participate in some of the RSV vaccine trials occurring soon at RCR.  Call 585-288-0890 to see if you qualify for one today!



RCR Sponsors the Mary Cariola 2018 Walking on Sunshine

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On Sunday September 23, join Mary Cariola and Rochester Clinical Research for the 2018 Walking on Sunshine event.RCR is a Diamond Sponsor and several of the RCR team will be there in support. Each year, RCR walks on “Team David” in memory of former staff member and Patricia’s husband, David Larrabee. Patricia Larrabee, Founder and CEO of RCR, is the Chair on the Board of Directors of Mary Cariola Children’s Center and the RCR staff are avid supporters of this annual fund raiser.

Mary Cariola is a private, non-profit agency and is regarded as a leader in providing education, residential programs and other services for individuals with disabilities. The Center was the first in the nation to have a sensory room, and opened the state’s first group home for children and youth with significant behavior management needs.

The walk will raise funds to support over 500 children and youth with multiple disabilities and complex medical needs. With the support from the community, Mary Cariola will be able to purchase specialized adaptive equipment, provide individualized assistance for our residents, support our non-funded music therapy department and navigate daily challenges for every student and family with the help of licensed social worker.

Registration for the walk begins at 9:30AM with an Opening Ceremony starting at 10:15AM. The walk will be held at Veterans Memorial Park located at 3100 Atlantic Avenue in Penfield, NY. If you decide to register, you can choose from a short Family Friendly Walk or a longer Wellness Walk. Activities include live music, family activities, raffles, team mascots, team photos, kickoff breakfast, celebration lunch and much more. Register for the event here. 



It’s National Immunization Awareness Month

Happy National Immunization Awareness Month. Vaccines prevent diseases that can be dangerous and even deadly. Vaccines are your best shot to reduce your risk of infection by working with your body’s natural defenses to help you safely develop immunity to disease. When germs invade your body, they multiply and attack causing your illness. The immune system fights the infection and after, the body has a supply of cells that help recognize and fight that disease in the future. Vaccines are a biological preparation that improves immunity to a particular disease. Many times, a  vaccine contains an agent that resembles a disease-causing microogranism, and is often made from weakened or killed form of the disease. The vaccine allows the body’s immune system to recognize the agent so in the future it knows it is foreign and that it should destroy it to keep you from getting sick.

So far, vaccines have almost totally eliminated these infectious diseases in the United States. Between 1990 and 2015, the number of children under the age of 5 dying each year declined over 12 million to 5.9 million, partly due to the impact of vaccination campaigns.

See below the list of diseases that have almost been totally eliminated in the United States.

  • Diphtheria
  • H. Influenza
  • Hepatitis A
  • Hepatits B
  • Measels
  • Mumps
  • Pertussis
  • Pneumococcal Disease
  • Congenital Rubella
  • Rubella
  • Polio
  • Small Pox
  • Tetanus
  • Varicella

Since viruses are constantly mutating, vaccine development is an important tool in protecting against new strains. Hence the importance of vaccine research studies and development.  It can take upwards of 20 years to develop a new vaccine, and we need your help today! Join a clinical study at Rochester Clinical Research to help the search of new vaccines to prevent disease. Research also can show how to be better administer and develop a vaccination that is stronger or can have better protection against a particular disease or illness. RCR is currently enrolling for studies involving RSV Vaccine, Flu Vaccine and Pneumococcal Disease Vaccine and more. Call 585-288-0890 to see if you qualify.

Watch the below videos from the CDC and  Department of Health & Human Services that talk about how vaccines are your best shot to be protected against these diseases.

Pneumococcal Vaccines

Shingles Vaccine

Whopping Cough Vaccines



RCR Volunteers at FoodLink, Inc.

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On Thursday, August 9th, we closed our office early so everyone at Rochester Clinical Research could volunteer at Foodlink, Inc.. At Rochester Clinical Research, we feel it is important to give back to the larger community. We strive to be a good corporate citizen, and our employees are engaged in a wide range of volunteer endeavors.

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Foodlink Inc. is a regional food hub and the Feeding America food bank serving Allegany, Genesee, Livingston, Monroe, Ontario, Orleans, Seneca, Wayne, Wyoming, and Yates counties. Their operations target the root causes of hunger by distributing food to a network of human service agencies and serving meals through their commercial kitchen. In the United States, 1 in 7 people are hungry including more than 1 in 5 children.

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Rochester Clinical Research was excited to get our hands dirty, and get to work as soon as we got there. Since we volunteered in the Warehouse/Distribution Center, we sorted through donated food, performed safety checks and helped assemble boxes of food for those in need. Before sorting, we had to dispose of product for a variety of reasons to abide by strict food safety standards. Once we went through expired or damaged items, we sorted the items by type, maintaining the specific weight limit per box. Overall, it was a great afternoon. We left feeling good about being a part of the 17 million pounds of food distributed through Foodlink each year and closer as a team.



RCR Offers Most Migraine Studies in the Country

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Rochester Clinical Research is proud to have consistently provided the Greater Rochester Area access to clinical research studies since 1994.  With each new clinical research study we take on, we are able to help advance new medical treatments and improve quality of life for our volunteers. We are proud to be currently providing the most migraine study options in the country (when compared to other clinical research sites). This gives our volunteers access to the most research study prevention and treatment medications, devices and therapies for migraines. Which could be better migraine treatment and prevention options than currently available.

Currently Rochester Clinical Research is enrolling volunteers for:

  • Oral Medication used for migraine headaches
  • Natural Nasal Spray used for migraine prevention
  • Oral Medication in the form of a dissolving tablet used for migraine prevention
  • Injected Migraine Medication used for migraine prevention

Rochester Clinical Research is also in the randomization phase of 5 additional migraine studies. Randomization is a step in a clinical trial where the volunteer has received the study drug or placebo and we have completed enrollment for that particular study.

If you suffer from migraines and would like to participate in a migraine research study, be sure to call 585-288-0890 to see if you qualify today for any of our studies!



Migraines: The Battle For A Cure

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On July 10th at the Strathallan Hotel, Dr. Joseph Mann and Rochester Clinical Research presented Migraines: The Battle for a Cure. Over 110 people came to hear Dr. Mann present as well as participate in a live question and answer portion of the evening. The presentation gave insight on why migraines occur, how migraines affects your life and available treatments options.

Migraines can take many forms, and many times individuals will refer their migraine as just a headache or pain. Migraines can be bilateral, unilateral, pulsing or non-pulsing. You can experience migraine pain in peripheral locations such as your neck or in your sinus area. Next, Dr. Mann discussed the migraine phases and the importance of identifying the earliest stages so you can avoid the advanced headache/migraine and postdrome phase.

Now that you can identify a migraine, what causes them? Dr. Mann reviewed two different causes including Cortical Spreading Depression (which occurs in clinically silent areas of the cortex) and dysfunction of brainstem nuclei which might exert a permissive role by favoring central trigeminal hyper-excitability.

Preventing migraines is the first form of treatment. The goal of prevention is to decrease the intensity and duration of pain and most bothersome symptoms. It allows the individual to decrease disability and use of acute medications.  Preventing also takes away the unpredictability. Unpredictability leads to stress and fear for future disruptive attacks which can result to a decrease in quality of life. Most importantly, prevent decreases the risk to turning your migraines into chronic migraines which may lead to changes in the brain.  Prevention can begin by learning what triggers your migraines, and avoiding them. Triggers can include stress, hunger, sleep disturbance, dehydration, diet, environmental stimuli, as well as changes in estrogen levels in women.

Treatment is a second options after prevention.  There are several FDA approved migraine treatments available on the market, however not everyone is a good candidate. Botox, Cefaly Tens Device, Triptans, and many others have been available. The newest approved migraine treatment is Aimovig (erenumab) which is a type of monoclonal antibody treatment. It resembles antibodies that the body naturally produces to bind to infectious pathogens. Since the CGRP widens blood vessels and can contribute to inflammation and pain transmission. Aimovig is delivered once a month with an EpiPen like injector. It works by the block the receptor for CGRP, reducing pain.  See below an illustration of how Aimovig works.

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As another care option, Rochester Clinical Research also addresses patient’s dissatisfaction with current preventatives and treatments. Our goal is to improve efficacy, provide better safety and tolerability, and provide faster onset and longer duration compared to current available medications. Right now, Rochester Clinical Research is offering several clinical research trials that may treat our migraines. Trials include a Natural Nasal Spray, an Oral migraine medication (a disolving tablet), an injection medication (once per month), and many other different trials coming up this fall. All of our studies do not require health insurance and compensation may be available for time and travel if you qualify. Each study has very specific inclusions exclusions to protect you and your health. Our Doctors and Nurses monitor your health closely and work with your primary care physician. Signing up is easy. Click on “RCR Studies – Currently Enrolling Studies” to see available studies. Find a study that interests you? See if you qualify by clicking the “See if you Qualify” button or call 585-288-0890 to speak with one of our recruiters.

Want to hear more from the event? Check out several of our Facebook Live Videos from the evening on our Facebook Page. 



RCR Helps Approval of Ebola Vaccine Use in DRC

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Rochester Clinical Research is proud to have helped approve the Merck Ebola Vaccination Clinical Trials. During the study, it was 100% successful leading to the approval of using it in the Democratic Republic of Congo where a deadly outbreak has occured resulting in 50 cases and 25 deaths this spring. Over 7,500 doses have been sent to the DRC which is expected to be extremely helpful in the outbreak. Emergency teams and the World Health Organization (WHO) are administering the vaccine which were donated by Merck to many individuals in the DRC, especially it’s capital.

A big thank you to all of our volunteers who helped make this study vaccine available to people in the Democrative Republic of Congo. It could not have happened without you.

Read more about Ebola Vaccination in DRC Here. 

 



“Migraines: The Battle for a Cure” on July 10 at 6PM at the Strathallen Hotel

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The battle is not over in finding the right preventative and treatment for disabling and frustrating migraine attacks. In the United States alone, over 37 million men, women and children live with the burden of unpredictable migraine attacks. “The majority of migraine sufferers do not get the relief they need from current migraine medications” states experienced Migraine Practitioner, Dr. Joseph Mann.  Rochester Clinical Research offers a multitude of treatment options, that are not yet available to the general public including different administered medications and devices that can make migraines less severe, reduce the frequency of migraine attacks and improve quality of life.

“Migraines: The Battle for a Cure” will discuss what causes migraines and what is being offered on the front lines here at Rochester Clinical Research as near-cures, alternative treatments and new devices that are available for thousands of sufferers. The event will be hosted on July 10th at 6:00PM at the Strathallen Hotel (550 East Avenue Rochester, NY). Registration will be required and space is limited to the first 150 registrants. Email your name, number attending and phone number to lgrizard@rcrclinical.com to register.

Currently available migraine medications, often bring negative side effects including nausea, vomiting or simply no relief. Rochester Clinical Research is conducting five investigational research studies each with a unique treatment prevention that may be better received in patients. These include an all-natural nasal spray. Similar to a probiotic, it enhances your immune system and can help prevent migraine headaches. Rochester Clinical Research also provides cutting-edge technology in migraine management with several device options controlled directly from your smart phone. There are a limited number of openings available to try these exclusive research study medication options, so migraine sufferers are encourage to attend  ”Migraines: The Battle for a Cure” to learn more and sign up.

 On May 31, 2018 the first medicine solely designed to prevent migraines was approved, ushering in a new era in the treatment of migraines. Rochester Clinical Research and nationally recognized neurologist and migraine specialist, Dr. Mann, are on the forefront in the search for similar new preventatives and acute treatments for the most common neurological disease. “It’s not just a headache. Migraines are still widely underdiagnosed and undertreated. If you have a disabling headache with nausea and light sensitivity, you most likely have a migraine” says Dr. Joseph Mann.

 If you suffer from migraines, this is an event you won’t want to miss. For more information or to register please call 585-288-0890.



Rochester Clinical Research Celebrates “Clinical Trial Day”

 

 

 

 

Happy Clinical Trial Day! 

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Everyone at Rochester Clinical Research celebrated Clinical Trial Day on Monday, May 21st. At RCR, we proudly conduct clinical research studies through our outstanding volunteers from Rochester, New York. The team loves being a part of Clinical Research because they not only are helping improve medicine but make a difference in many peoples’ lives.

Join the cause and volunteer today since volunteering for clinical research trials advances medicine and saves lives. 

We offer three easy steps to signing up:

1. Selecting a trial

2. Seeing if you qualify for the trial

3. Registering to begin the process

If you are new to the idea of volunteering for clinical trials, or to Rochester Clinical Research, you will probably want to know more. It’s all here on the website or give us a call at 585-288-0890.

If you have volunteered with us before, thank you for your dedication to tomorrow’s medicine. We hope to see you again soon.



Migraines with Mann

Dr. Joseph Mann is a board certified neurologist with a sub-specialty in headache medicine. We sat down with him and talked about Migraines. Check out his insights on everything migraines in this 5 part video series on our youtube page.

 

And be sure to see if you qualify for our current migraine studies



How informed consent removes the ‘guinea pig’ stigma from clinical research

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When, in 2016, Mary Dinnan, RPA-C retired from practicing primary care and joined the team at Rochester Clinical Research, she quickly realized how much her day-to-day work in private practice had been influenced by clinical research.

“I started to think — after having done primary care for 40 years — how much of what we do and did was the result of clinical trial work,” she said.

At RCR, clinical trials may involve vaccines for potential pandemics, but oftentimes they involve treatments for more commonplace conditions, including osteoarthritis, migraine or weight loss — things that may affect a friend, neighbor or loved one.

“These are normal issues that people deal with on a daily basis,” said Dinnan, adding that clinical research also informs recommendations doctors, Nurse Practitioners, and PAs give for common, potentially life-saving health screenings.

 “If I am advising someone to get a colonoscopy at 50, I don’t make that up — that is the result of somebody doing trials to determine when that type of intervention is necessary,” she said.

Dinnan is passionate about helping the public better understand the importance of clinical research — and breaking down the stigma that participants are “guinea pigs.”

All clinical trials include an in-depth process of learning key facts before an individual can decide to participate. Informed consent, as it’s called, continues throughout the study, said Dinnan.

“They have to understand what they’re signing up for,” she said. “And informed consent can be withdrawn at any time, so if you decide at any time that you no longer want to participate, it’s not a binding legal contract.”

Read full article here.



The Burdens of a Migraine

If you’ve ever tried to make it through a day of work or school with a headache, you know how much pain can disrupt your everyday routines. Now imagine having headache pain several times a month — or more. That’s a common occurrence for the 39 million Americans suffering from migraine, a neurological disease that can not only cause headache pain but also sensitivity to light and sound, extreme nausea, vomiting and disturbed vision.

“Migraines are more than just headaches,” said Dr. Joseph J. Mann, the Neurology and Headache Medicine Investigator at Rochester Clinical Research. Migraines involve both electrical and chemical processes in the brain, he said, causing excruciating pain, disability and burden upon sufferers.

According to the World Health Organization, migraine is the sixth leading cause of LYD (years living with disability) worldwide, and a 2015 study found that migraine and headaches are leading causes of both outpatient and emergency room visits in the US. And yet, there are only four preventative migraine treatments approved by the US Food and Drug Administration. Mann and his colleagues are working to increase that number.

Full Article here



How Healthy Volunteers Shape Medicine’s Future

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Everyday heroes — that’s the name that Dr. Matthew Davis and his team at Rochester Clinical Research have for those who participate in their clinical research studies. RCR’s research on these healthy adults helps prevent, detect, diagnose, control and treat illnesses.

“We’re always in need of healthy people willing to help out their fellow man,” said Davis of the work he has done at RCR for the last two decades. “There’s really no medical progress made unless healthy volunteers step up to the plate and volunteer to try new things.”

Whether it’s a vaccine to prevent a potential avian flu pandemic or a new diabetes medication, every treatment is tested in healthy adults before being used in affected populations, said Davis, RCR’s medical director. Since 1994, more than 10,000 healthy volunteers have helped RCR in more than 600 clinical research studies.

Participating in a clinical trial is not time-consuming or difficult, though each study differs, according to RCR. Studies range from months up to a year or sometimes more. However, volunteers, who are compensated for their time, find the study takes less time as it goes on. Davis said that the first appointment — with sessions on informed consent to go over any risks and side effects, a comprehensive medical exam and laboratory testing — may take 90 minutes to two hours, while subsequent visits may take only 10 to 20 minutes every few weeks or month.

Volunteers not only actively support their own health care, but they also help others — perhaps even a friend, neighbor or loved one — by being a part of ground-breaking medical research. On a personal level, they have access to new research and treatments not yet available to the public.

“They’re helping the rest of us,” Davis said. That’s also what motivated Davis, a board-certified family physician and Air Force active-duty veteran, to become a researcher. “You feel like you’re part of a bigger picture,” said Davis, who has been a principal investigator or sub-investigator in more than 500 studies.

Some of the diseases Davis and RCR studies — like Dengue fever or Zika virus — are rarely if ever found in Rochester or much of the United States. But studies of those diseases also require healthy adult volunteers.

 He cites an outbreak that did affect the US, the Spanish flu of 1918 and 1919. That pandemic killed more than 50 million worldwide and infected more than 10 times that many, according to the Centers for Disease Control and Prevention. While most Americans weren’t alive to remember that outbreak, it’s not one we should forget, said Davis. “Most experts say it will happen again at some point — the question is when,” he said.

Davis emphasizes the important role that volunteers play in these and all studies RCR conducts. No matter how long research has been going on, no matter how much promise a drug or treatment may have, it all stops without healthy volunteers. Every study needs enough volunteers to statistically determine whether something is a good treatment, which is why Davis reiterates how unselfish such participation is.

“Really, they are doing something that may not benefit them directly, but may have an impact five, 10 years down the line,” he said.



How to Find Arthritis Relief

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Cold weather can really do a number on the already painful aches of arthritis. Below are a few tips to finding arthritis relief this winter.

  1. Dress Safe and Warm
    Keep aching hands in gloves, add layers over knees and legs. If you’re going outside wear solid, supportive shoes with good treads and avoid icy surfaces.
  2. Stay Hydrated
    Even mild dehydration might make you more sensitive to pain. You can also find relief from a warm bath or swimming pool, but don’t go right out in the cold afterwards – let your body’s temperature normalize a bit.
  3. Stay Active
    Winter seems like a great time to “hibernate” but staying active can really help your arthritis. Many people find that as their activity levels go up, and weight goes down, their arthritis improved. Try to come up with an indoor exercise plan – treadmills or elipticals, or even a walk at the mall.
  4. Take your vitamins
    Low levels of Vitamin D could be adding to your pain. There are many other supplements that have been successful in helping with arthritis pain as well, from fish oil to acetaminophen. Consult your doctor to find the right thing for you.
  5. Seek treatment
    Visit a doctor, get a massage, try acupuncture, or participate in a clinical trial – find what works for you.

Rochester Clinical Research has several currently enrolling clinical trials for those suffering from arthritis. See if you qualify today!



10 Tips and Tricks to Avoid the Flu

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With such a severe flu season this year. Here are 10 tips and tricks to prevent the spread of germs brought to you by the CDC!

  1. Avoid close contact to anyone who is sick
  2. Don’t be a hero – if you are sick, stay home from work or school!
  3. Cover your mouth and nose when you sneeze or cough
  4. Clean your hands often – soap and water or alcohol-based hand rub will do
  5. Avoid touching your eyes, nose, or mouth when possible
  6. Keep surfaces clean at your home, work, or school
  7. Drink plenty of fluids
  8. Eat nutritious foods
  9. Get plenty of sleep
  10. Find ways to manage your stress

Interested in participating in a universal vaccine study? Click here for more information!



‘Tis the season of giving at RCR!

Christmas Spirit is in the air at Rochester Clinical Research. This year, RCR partnered with Mary Cariola Children’s Center to give one family a spectacular Christmas filled with lots of gifts! With over 30 gifts generously donated by our staff, we hope to spread the Christmas Cheer to those less fortunate than us. Happy Holidays from Rochester Clinical Research!

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Patient Spotlight: Gayle

Rochester Clinical Research has amazing volunteers that help to advance medicine for the future. RCR would like to put a spotlight on our volunteers to show our appreciation!

Meet Gayle! As a long time sufferer of migraines, Gayle participated in a migraine study that RCR conducted this past year.



New Research being conducted to Prevent the Most Common Cause of Hospital-acquired infection.

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Clostridium difficile (C. diff) is one of the most common causes of healthcare-related infections. It is estimated that each year in the United States, about a half million people get sick from C. difficile, and in recent years, C. difficile infections have become more frequent, severe, and difficult to treat.

C. diff is a type of bacteria that lives in the human intestines. Its spores can survive outside of the body for months. These spores are resistant to cleaning and are most commonly transmitted in healthcare settings. People can become infected by touching surfaces that are contaminated or by coming into contact with a healthcare worker that has the bacteria or spores on their hands.

People most at risk of getting sick due to C. diff are those who are taking antibiotics, being treated in a healthcare facility, the elderly and people who are already ill. This infection can cause symptoms that include frequent diarrhea, inflammation of the colon, fever, nausea and abdominal pain; in severe cases it can be life-threatening.

Rochester Clinical Research is conducting a study to evaluate the safety and efficacy of an investigational vaccine in reducing the chances of getting sick due to C. diff. The knowledge gained from this study may help others in the future. Eligible participants will receive study related tests and procedures at no cost and compensation may be available.  Call 585-288-0890 or email volunteer@rcrclinical.com to learn how you can help contribute to this important research study.

Check out our C. Diff study spotlight on WXXI News.



Patient Spotlight: Roselyn

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RCR: How many/what studies have you participated in?

Roselyn: I’ve done 3-4 over a few years. The last one I remember was a study on a daily injection for Osteoporosis where I ended up being one of the people to get the placebo.

RCR: Why did you initially decide to participate in this study?

Roselyn: I’m a very altruistic person. I believe when I leave this world I will take my body with me, so I’d like to use it to help humanity while I am still here.

RCR: What did you enjoy about the study?

Roselyn: Nothing was difficult, everything was easy from start to finish

RCR: Is there anything that stuck out to you about RCR specifically?

Roselyn: The Nurses were very professional and gentle.

RCR: What would you like to say to people who are hesitant about Clinical Trials?

Roselyn: That they are helping the future. They are helping future generations not have to deal with diseases that we’ve dealt with in the past.



RCR Commercial

Check out our latest commercial

Produced in collaboration with Sundance Marketing, this video titled You and Me, represents what Rochester Clinical Research is all about, our volunteers. Without our loyal volunteers, we would be unable to live out our mission of – Advancing Medicine and Changing Lives.



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