Rochester Clinical Research Celebrates “Clinical Trial Day”
Happy Clinical Trial Day!
Everyone at Rochester Clinical Research celebrated Clinical Trial Day on Monday, May 21st. At RCR, we proudly conduct clinical research studies through our outstanding volunteers from Rochester, New York. The team loves being a part of Clinical Research because they not only are helping improve medicine but make a difference in many peoples’ lives.
Join the cause and volunteer today since volunteering for clinical research trials advances medicine and saves lives.
We offer three easy steps to signing up:
1. Selecting a trial
2. Seeing if you qualify for the trial
3. Registering to begin the process
If you are new to the idea of volunteering for clinical trials, or to Rochester Clinical Research, you will probably want to know more. It’s all here on the website or give us a call at 585-288-0890.
If you have volunteered with us before, thank you for your dedication to tomorrow’s medicine. We hope to see you again soon.
Migraines with Mann
Dr. Joseph Mann is a board certified neurologist with a sub-specialty in headache medicine. We sat down with him and talked about Migraines. Check out his insights on everything migraines in this 5 part video series on our youtube page.
And be sure to see if you qualify for our current migraine studies
How informed consent removes the ‘guinea pig’ stigma from clinical research
When, in 2016, Mary Dinnan, RPA-C retired from practicing primary care and joined the team at Rochester Clinical Research, she quickly realized how much her day-to-day work in private practice had been influenced by clinical research.
“I started to think — after having done primary care for 40 years — how much of what we do and did was the result of clinical trial work,” she said.
At RCR, clinical trials may involve vaccines for potential pandemics, but oftentimes they involve treatments for more commonplace conditions, including osteoarthritis, migraine or weight loss — things that may affect a friend, neighbor or loved one.
“These are normal issues that people deal with on a daily basis,” said Dinnan, adding that clinical research also informs recommendations doctors, Nurse Practitioners, and PAs give for common, potentially life-saving health screenings.
Dinnan is passionate about helping the public better understand the importance of clinical research — and breaking down the stigma that participants are “guinea pigs.”
All clinical trials include an in-depth process of learning key facts before an individual can decide to participate. Informed consent, as it’s called, continues throughout the study, said Dinnan.
“They have to understand what they’re signing up for,” she said. “And informed consent can be withdrawn at any time, so if you decide at any time that you no longer want to participate, it’s not a binding legal contract.”
The Burdens of a Migraine
If you’ve ever tried to make it through a day of work or school with a headache, you know how much pain can disrupt your everyday routines. Now imagine having headache pain several times a month — or more. That’s a common occurrence for the 39 million Americans suffering from migraine, a neurological disease that can not only cause headache pain but also sensitivity to light and sound, extreme nausea, vomiting and disturbed vision.
“Migraines are more than just headaches,” said Dr. Joseph J. Mann, the Neurology and Headache Medicine Investigator at Rochester Clinical Research. Migraines involve both electrical and chemical processes in the brain, he said, causing excruciating pain, disability and burden upon sufferers.
According to the World Health Organization, migraine is the sixth leading cause of LYD (years living with disability) worldwide, and a 2015 study found that migraine and headaches are leading causes of both outpatient and emergency room visits in the US. And yet, there are only four preventative migraine treatments approved by the US Food and Drug Administration. Mann and his colleagues are working to increase that number.
Full Article here
How Healthy Volunteers Shape Medicine’s Future
Everyday heroes — that’s the name that Dr. Matthew Davis and his team at Rochester Clinical Research have for those who participate in their clinical research studies. RCR’s research on these healthy adults helps prevent, detect, diagnose, control and treat illnesses.
“We’re always in need of healthy people willing to help out their fellow man,” said Davis of the work he has done at RCR for the last two decades. “There’s really no medical progress made unless healthy volunteers step up to the plate and volunteer to try new things.”
Whether it’s a vaccine to prevent a potential avian flu pandemic or a new diabetes medication, every treatment is tested in healthy adults before being used in affected populations, said Davis, RCR’s medical director. Since 1994, more than 10,000 healthy volunteers have helped RCR in more than 600 clinical research studies.
Participating in a clinical trial is not time-consuming or difficult, though each study differs, according to RCR. Studies range from months up to a year or sometimes more. However, volunteers, who are compensated for their time, find the study takes less time as it goes on. Davis said that the first appointment — with sessions on informed consent to go over any risks and side effects, a comprehensive medical exam and laboratory testing — may take 90 minutes to two hours, while subsequent visits may take only 10 to 20 minutes every few weeks or month.
Volunteers not only actively support their own health care, but they also help others — perhaps even a friend, neighbor or loved one — by being a part of ground-breaking medical research. On a personal level, they have access to new research and treatments not yet available to the public.
“They’re helping the rest of us,” Davis said. That’s also what motivated Davis, a board-certified family physician and Air Force active-duty veteran, to become a researcher. “You feel like you’re part of a bigger picture,” said Davis, who has been a principal investigator or sub-investigator in more than 500 studies.
Some of the diseases Davis and RCR studies — like Dengue fever or Zika virus — are rarely if ever found in Rochester or much of the United States. But studies of those diseases also require healthy adult volunteers.
Davis emphasizes the important role that volunteers play in these and all studies RCR conducts. No matter how long research has been going on, no matter how much promise a drug or treatment may have, it all stops without healthy volunteers. Every study needs enough volunteers to statistically determine whether something is a good treatment, which is why Davis reiterates how unselfish such participation is.
“Really, they are doing something that may not benefit them directly, but may have an impact five, 10 years down the line,” he said.
How to Find Arthritis Relief
Cold weather can really do a number on the already painful aches of arthritis. Below are a few tips to finding arthritis relief this winter.
- Dress Safe and Warm
Keep aching hands in gloves, add layers over knees and legs. If you’re going outside wear solid, supportive shoes with good treads and avoid icy surfaces.
- Stay Hydrated
Even mild dehydration might make you more sensitive to pain. You can also find relief from a warm bath or swimming pool, but don’t go right out in the cold afterwards – let your body’s temperature normalize a bit.
- Stay Active
Winter seems like a great time to “hibernate” but staying active can really help your arthritis. Many people find that as their activity levels go up, and weight goes down, their arthritis improved. Try to come up with an indoor exercise plan – treadmills or elipticals, or even a walk at the mall.
- Take your vitamins
Low levels of Vitamin D could be adding to your pain. There are many other supplements that have been successful in helping with arthritis pain as well, from fish oil to acetaminophen. Consult your doctor to find the right thing for you.
- Seek treatment
Visit a doctor, get a massage, try acupuncture, or participate in a clinical trial – find what works for you.
Rochester Clinical Research has several currently enrolling clinical trials for those suffering from arthritis. See if you qualify today!
- Osteoarthritis of the knee (single)
- Osteoarthritis of the knee (bilateral)
- Osteoarthritis of the shoulder
10 Tips and Tricks to Avoid the Flu
With such a severe flu season this year. Here are 10 tips and tricks to prevent the spread of germs brought to you by the CDC!
- Avoid close contact to anyone who is sick
- Don’t be a hero – if you are sick, stay home from work or school!
- Cover your mouth and nose when you sneeze or cough
- Clean your hands often – soap and water or alcohol-based hand rub will do
- Avoid touching your eyes, nose, or mouth when possible
- Keep surfaces clean at your home, work, or school
- Drink plenty of fluids
- Eat nutritious foods
- Get plenty of sleep
- Find ways to manage your stress
Interested in participating in a universal vaccine study? Click here for more information!
‘Tis the season of giving at RCR!
Christmas Spirit is in the air at Rochester Clinical Research. This year, RCR partnered with Mary Cariola Children’s Center to give one family a spectacular Christmas filled with lots of gifts! With over 30 gifts generously donated by our staff, we hope to spread the Christmas Cheer to those less fortunate than us. Happy Holidays from Rochester Clinical Research!
Patient Spotlight: Gayle
Rochester Clinical Research has amazing volunteers that help to advance medicine for the future. RCR would like to put a spotlight on our volunteers to show our appreciation!
Meet Gayle! As a long time sufferer of migraines, Gayle participated in a migraine study that RCR conducted this past year.
New Research being conducted to Prevent the Most Common Cause of Hospital-acquired infection.
Clostridium difficile (C. diff) is one of the most common causes of healthcare-related infections. It is estimated that each year in the United States, about a half million people get sick from C. difficile, and in recent years, C. difficile infections have become more frequent, severe, and difficult to treat.
C. diff is a type of bacteria that lives in the human intestines. Its spores can survive outside of the body for months. These spores are resistant to cleaning and are most commonly transmitted in healthcare settings. People can become infected by touching surfaces that are contaminated or by coming into contact with a healthcare worker that has the bacteria or spores on their hands.
People most at risk of getting sick due to C. diff are those who are taking antibiotics, being treated in a healthcare facility, the elderly and people who are already ill. This infection can cause symptoms that include frequent diarrhea, inflammation of the colon, fever, nausea and abdominal pain; in severe cases it can be life-threatening.
Rochester Clinical Research is conducting a study to evaluate the safety and efficacy of an investigational vaccine in reducing the chances of getting sick due to C. diff. The knowledge gained from this study may help others in the future. Eligible participants will receive study related tests and procedures at no cost and compensation may be available. Call 585-288-0890 or email email@example.com to learn how you can help contribute to this important research study.
Check out our C. Diff study spotlight on WXXI News.
Patient Spotlight: Roselyn
RCR: How many/what studies have you participated in?
Roselyn: I’ve done 3-4 over a few years. The last one I remember was a study on a daily injection for Osteoporosis where I ended up being one of the people to get the placebo.
RCR: Why did you initially decide to participate in this study?
Roselyn: I’m a very altruistic person. I believe when I leave this world I will take my body with me, so I’d like to use it to help humanity while I am still here.
RCR: What did you enjoy about the study?
Roselyn: Nothing was difficult, everything was easy from start to finish
RCR: Is there anything that stuck out to you about RCR specifically?
Roselyn: The Nurses were very professional and gentle.
RCR: What would you like to say to people who are hesitant about Clinical Trials?
Roselyn: That they are helping the future. They are helping future generations not have to deal with diseases that we’ve dealt with in the past.
Check out our latest commercial
Produced in collaboration with Sundance Marketing, this video titled You and Me, represents what Rochester Clinical Research is all about, our volunteers. Without our loyal volunteers, we would be unable to live out our mission of – Advancing Medicine and Changing Lives.
Saying “It’s too late for me to quit smoking” is just an excuse
20 Minutes after quitting…
your heart rate drops to a normal level
12 hours after quitting…
the carbon monoxide level in your blood drops to normal
2 weeks – 3 months after quitting…
your risk of having a heart attack drops and your lung function improves
1-9 months after quitting…
your coughing and shortness of breath decrease
1 year after quitting…
your added risk of coronary heart disease is half that of current smokers
5-15 years after quitting…
your risk of having a stroke is half that of a smoker’s and your risk of getting cancer of the mouth, throat, or esophagus is half that of a smoker’s
10 years after quitting…
your risk of getting bladder cancer or dying from lung cancer is about half that of a smoker’s. your risk of getting cervical cancer or cancer of the larynx, kidney or pancreas decreases
15 years after quitting…
your risk of coronary heart disease is the same as that of a non smoker
Contact Rochester Clinical Research for more information on tips and tricks to quitting smoking 585-288-0890 or Text “info” to 87888
Local Neurologist and Headache Specialist, Dr. Joseph Mann and Rochester Clinical Research Join Forces
Dr. Joseph Mann, recipient of 2016 Headache Practitioner of the Year Award, has joined on as part of the Rochester Clinical Research staff.
Rochester, NY– Rochester Clinical Research is proud to announce that Dr. Joseph Mann, a prominent Rochester neurologist, has joined on as part of the staff. Dr. Mann was recently awarded the 2016 Headache Practitioner of the Year Award by the National Headache Society. Dr. Mann is board certified in both neurology and psychiatry and has sub-specialty certification in Headache Medicine.
With this new addition, Rochester Clinical Research will be able to not only continue with its long history of migraine research, but explore new areas of migraine research and other neurological and psychiatric areas such as: ADD, mild depression, mild cognitive impairment, as well as other headache disorders.
“We couldn’t be more proud to have Dr. Joseph Mann as part of the RCR staff. He’s an incredibly gifted neurologist and we’ve always admired the work he does and the relationships that he builds with his patients and colleagues. I look forward to working more closely with him and pursuing new and exciting opportunities” said Adam Larrabee, President of Rochester Clinical Research.
About Rochester Clinical Research
RCR was founded in 1994 to provide residents of the Greater Rochester Area access to clinical research studies and advance new medical treatments. Our unwavering commitment to providing efficient, friendly and caring service has helped us in becoming one of the leading research sites in the United States, noted for a large, loyal group of volunteers and frequent studies. RCR has conducted more than 650 research studies, involving more than 15,000 volunteers. For more information, visit www.RCRclinical.com.
Protected: 5 Questions and Answers: C. Difficile
What do you really know about C. Diff? 90% of deaths related to C. Diff occur in individuals who are 65 years of age and older, and 1 in 5 people who are infected have recurring infections. In total, C. Diff accounts for roughly 14,000 deaths per year. Read on to learn more about C. Diff and an opportunity to help find a vaccine.
- How can you get C. Diff?
- Well, those at the highest risk are the elderly population, and those taking antibiotics. Most C. Diff cases are a result of ineffective, or lack of infection prevention and control measures.
- How do you know if you have it?
- Symptoms include fever, lack of appetite, nausea, watery diarrhea, and abdominal pain/tenderness.
- How does taking antibiotics contribute to C. Difficile?
- Elevated doses of certain antibiotics used over an extended period of time can increase the probability of contracting a C. Diff infection because antibiotics change the composition of bacteria in the gut. When there are fewer bacteria in the gut, it creates room for C. Diff to come in and produce toxins.
- How can you prevent C. Diff?
- Careful use of antibiotics, and taking the necessary infection prevention and control measures.
- Is C. Diff fatal?
- Diff can cause mild diarrhea, to life-threatening conditions such as: bowel perforation, sepsis, and even death.
Rochester Clinical Research is now seeking interested volunteers for an investigational study for a C. Diff vaccine. If you’re 50 years of age or older and fall within one or more of the categories below, you may qualify.
- Visited the hospital at least once within the past 12 months, for 2 or more nights
- Visited the emergency room at least twice within the past 12 months
- Visited the doctors at least 12 times within the past 12 months
- Live in a nursing facility
- Taken an antibiotic within the past 3 months
- Cannot have had C. Diff
- **Please note, other conditions may apply**
Please click on the link below or call 585-288-0890 to learn more or see if you qualify.
Ebola Vaccine – 100% Protection During Clinical Trial
Interested in reading more? Follow the link below!
Americas become first region to eliminate measles
Reuters: After a 22-year vaccination effort against the measles, the Pan American Health Organization said on Tuesday that The Americas has become the first region in the world to have eradicated measles. This is a tremendous accomplishment, given that measles continues to infect tens of thousands of people on a global scale.
12 Risk Factors of High Blood Pressure You Need to Know
There are many risk factors involved with high blood pressure, but the 12 listed below are among the most common. High blood pressure is a common condition where the long-term force of the blood against artery walls is high enough to cause health problems such as heart disease. Blood pressure is determined is by the amount of blood the heart pumps versus the amount of resistance to blood flow in the arteries. When increasing the volume of blood and narrowing the arteries, higher pressures arise – potentially resulting in high blood pressure.
- Age: As people age, the risk of high blood pressure is elevated. Around age 45, high blood pressure is more common in men. Women have a greater risk of developing high blood pressure after age 65.
- Race: High blood pressure is particularly common among African Americans, often developing at an earlier age than Caucasians.
- Family History: High blood pressure tends to be hereditary.
- Being Overweight/Obese: The more a person weighs, the more blood is required to supply oxygen and nutrients to tissues. As the volume of blood increases, so does the pressure on artery walls
- Lack of Physical Activity or Exercise: Individuals who are inactive tend to have higher heart rates. The higher your heart rate, the harder the heart must work – increasing the force on arteries.
- Use of Tobacco: Smoking or chewing tobacco has an immediate, temporary effect on your blood pressure. In addition, the chemicals in tobacco can potentially damage the lining of your artery walls – causing your arteries to narrow. This narrowing affect increases blood pressure. Secondhand smoke can also increase your blood pressure.
- High Sodium Diet: Having an excess of sodium in your diet causes your body to retain fluid, which contributes to an increase in blood pressure.
- Lack of Potassium in Your Diet: Potassium helps regulate the amount of sodium in your cells. Without enough, you may accumulate too much sodium in your blood.
- Prolonged Periods of Too Much Alcohol: Over time, excessive drinking can damage the heart. Having more than two drinks a day for man and more than one drink per day for women may affect blood pressure.
- Not Enough Vitamin D: While there are still uncertainties surrounding this statement, Vitamin D may affect an enzyme produced by your kidneys that affects blood pressure.
- Stress: High levels of stress may lead to a temporary increase in blood pressure. Attempting to alleviate stress through eating, drinking, or tobacco, you may contribute to problems with high blood pressure.
- Certain Chronic Conditions: Certain chronic conditions may increase the risk of high blood pressure, such as kidney disease, diabetes, and sleep apnea.
we are currently enrolling for a high blood pressure study. Follow the link below or give us a call at 585-288-0890 if you’d like to learn more about this opportunity.
Migraines – Not Just A “Bad Headache”
Migraines are often thought of as simply a “bad headache”. However, contrary to this common thinking, they’re not. A migraine is a collection of neurological symptoms – usually including a severe throbbing and recurring pain on one side of the head (in roughly 1/3 migraine attacks, both sides are affected). Migraine attacks last between 4 and 72 hours and often encompass at least one of the following symptoms:
- Visual disturbances
- Sensitivity to sound, light, touch and smell
- Tingling or numbness in the extremities or face
Migraines are an extraordinarily prevalent neurological disease, affecting 38 million men, women, and children in the U.S. Below are some facts that may surprise you…
You probably know more migraine sufferers than you may be aware of.
- Migraines are the 3rd most prevalent disease in the world
- Roughly 25% of households in the U.S. have at least 1 migraine sufferer
- 12% of the U.S. population (including children) suffers from migraines
- 18% of American women fall victim to migraines (compared to 6% of men)
- 10% of children experience migraines
- 80% of migraine sufferers have a family history of migraines
Migraines can be really, REALLY debilitating
- Migraines are the 8th most disabling illness in the world
- Every 10 seconds someone in the U.S. enters the emergency room complaining of head pain
- 4 million people have chronic daily migraine, having at least 15 migraine days per month
- 90% of migraine sufferers cannot work or function normally during their migraines
Migraines costs…A LOT
- Costs associated with migraines are estimated to be north of $36 billion in the U.S., for healthcare and lost productivity.
- Healthcare for households with a migraine sufferer are 70% higher than those without
- American employers lose more than $13 billion each year as a result of lost work days due to migraines
Migraines are still largely a medical mystery and is often undiagnosed
- In 2015 there were only 500 certified headache specialists in the U.S. and 38 million sufferers
- More than half of all migraine sufferers are never diagnosed with migraines
- Many migraine sufferers never seek medical attention for their pain
- Only 4% of migraine sufferers ever seek a headache specialist
Source: Migraine Research Foundation
10 Things You Should Know About Clinical Trials
1. What is a Clinical Trial?
A clinical research study or “trial” is a scientific study evaluating a new treatment that has shown promise in laboratory studies. It is through these studies or trials that doctors find new and better ways to prevent, detect, diagnose, control and treat illnesses.
2. Who can participate in a clinical trial?
Before joining a clinical trial, a participant must meet specific requirements in order to qualify. All clinical trials have guidelines about who can participate and these guidelines are based off of factors such as age, gender, previous treatment history, and other medical conditions. If you think you may be a good fit for a particular trial you should contact the research site and consult your doctor.
3. How long does it take a drug to go through the clinical trial process before it is publicly available?
The Food and Drug Administration (FDA) requires that clinical trials be performed on all new and improved medications before that new treatment becomes available for public use. It is only after many years of laboratory testing that drugs are approved to enter the clinical trial phases. In some cases it can take from 10-15 years for a drug to go through all phases of the clinical trial process.
4. What are the benefits of participating in a clinical trial?
A well designed and well executed clinical trial is a great way for eligible participants to play an active role in their own health care, gain access to new research treatments before they are widely available, and also help others by contributing to medical research.
5. What are the risks of participating in a clinical trial?
Like any other form of research, various uncertainties and unforeseen events can occur. In some cases participants may experience unpleasant side effects, and very rarely, may experience serious or even life-threatening side effects as a result of the treatment. This is why it’s always important to consult your doctor prior to participation.
6. Can someone stop participating in a clinical trial after it has begun?
A participant can leave a clinical trial at any time. When withdrawing from the trial, the participant should let the research team know about it, and the reasons for leaving the study.
7. What should someone consider before participating in a clinical trial?
- What is the purpose of the study?
- Who is going to be in the study?
- Why do researchers believe the new treatment being tested may be effective? Has it been tested before?
- What kinds of tests and treatments are involved?
- How do the possible risks, side effects and benefits in the study compare with my current treatment?
- How might this trial affect my daily life?
- How long will the trial last?
- Will hospitalization be required?
- Who will pay for the treatment?
- Will I be reimbursed for other expenses?
- What type of long-term follow up care is part of this study?
- How will I know that the treatment is working?
- Will results of the trials be provided to me?
- Who will be in charge of my care?
8. Does a person continue to work with a primary health care provider while in clinical trials?
Yes. Most clinical trials provide short-term treatments related to a designated illness or condition, but do not provide extended or complete health care. In addition, by having the health care provider work with the research team, the participant can ensure that other medications or treatments will not conflict with the study requirements.
9. Clinical trials need more participants!!
According to a recent article in The Wall Street Journal, fewer than 10% of Americans participate in clinical trials and nearly 40% of clinical trials are unable to find enough volunteers to meet their enrollment goals. When this happens, delays are caused in the clinical trial process which increases the amount of time it takes to bring new medications and drugs to the public.
10. Where can someone go to learn about what clinical research studies are currently available?
To find out what clinical research studies are available, people can visit www.clinicaltrials.gov, or www.RCRclinical.com to see some of the studies that are currently enrolling in the Rochester-area. You can also speak to someone on our recruitment team by calling (585) 288-0890.